Article

Olaparib reverses prostate cancer resistance to Rapamycin by promoting macrophage polarization towards the M1 phenotype

2024-11-26

Abstract excerpt

<title>Abstract</title> <p>Prostate cancer (PCa) is the most common non-cutaneous malignancy and the second leading cause of cancer-related death in men. Despite its prevalence, treatment outcomes are often unsatisfactory, necessitating the search for more effective therapeutic approaches. mTOR inhibitor Rapamycin (RAPA) has shown promise in managing PCa, but the emergence of resistance often undermines its long-...

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Literature Corpus work: 2a35949d-1605-5a2b-934d-ae2ae235f8d8
DOI: 10.21203/rs.3.rs-5399970/v1

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