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TNF⍰-mediated myeloid-instructed CD14 <sup>+</sup> CD4 <sup>+</sup> T cells within the tumor microenvironment are associated with poor survival in non-small cell lung cancer

2024-08-06

Abstract excerpt

The tumor microenvironment (TME) harbors a diverse array of innate and adaptive immune cells that can either support anti-tumor immunity or facilitate tumor progression. Among these, myeloid cells are key drivers of immunosuppression, yet therapeutic strategies targeting their function have achieved limited clinical success. A deeper understanding of the mechanisms by which immunosuppressive myeloid cells promote...

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Literature Corpus work
2ee40130-5760-5e01-8218-ae35c669ec89
DOI
10.1101/2024.08.02.606259
Open publication

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TNF⍰-mediated myeloid-instructed CD14 <sup>+</sup> CD4 <sup>+</sup> T cells within the tumor microenvironment are associated with poor survival in non-small cell lung cancerDOI 10.1101/2024.08.02.606259
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