Article
Genetic and environmental factors affecting Alzheimer's disease pathogenic mechanism : the role of sirtuins
2012-01-01
Abstract excerpt
Alzheimer's disease (AD) is the leading cause of senile dementia and the current lack of effective treatments provides a strong incentive for an improved therapeutic strategy. In particular, non-pharmacological treatments, such as calorie restriction (CR), were shown to be useful in delaying or preventing AD onset. This has given insight into the molecular pathways involved. Sirtuins (SIRT1-7) are evolutionary con...
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Identifiers and source
- Literature Corpus work
- 2ee09f97-8b31-529b-8b48-e05203789c88
- DOI
- 10.21954/ou.ro.0000eebf