Article

USF2 Knockdown Downregulates THBS1 to Inhibit the TGF-β Signaling Pathway and Reduce Pyroptosis in Sepsis-Induced Acute Kidney Injury

2020-12-16

Abstract excerpt

<title>Abstract</title> <p>BackgroundAcute kidney injury (AKI) is a serious complication of sepsis. This study was performed to explore the mechanism that THBS1 mediated pyroptosis by regulating TGF-β signaling pathway in sepsis-induced AKI.MethodsGene expression microarray related to sepsis-induced AKI was obtained from the GEO database, and the mechanism in sepsis-induced AKI was predicted by bioinformatics ana...

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Literature Corpus work: b446b7ca-6b8e-5a08-ae96-1f11dfab2216
DOI: 10.21203/rs.3.rs-126763/v1

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