Article

Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines

2019-05-31

Abstract excerpt

Targeted cancer therapies are powerful alternatives to chemotherapies or can be used complementary to these. Yet, the response to targeted treatments depends on a variety of factors, including mutations and expression levels, and therefore their outcome is difficult to predict. Here, we develop a mechanistic model of gastric cancer to study response and resistance factors for cetuximab treatment. The model capture...

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Identifiers and source

Literature Corpus work: 2eb65866-bf1b-5f61-abdd-73bd3eb4c63b
DOI: 10.1101/656967

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