Article

Matrix metalloproteinase activation and inhibition

1995-01-01

Abstract excerpt

Processes leading to the <i>in vitro</i> activation of progelatinase-A, progelatinase-B and procollagenase were examined. Progelatinase-A can be activated by treatment with 4-aminophenyl mercuric acetate or by matrilysin and collagenase. The former induces an intramolecular self-cleavage before further intermolecular cleavages generate the mature enzyme. Whilst matrilysin can process progelatinase-A to the mature...

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Literature Corpus work: 2e9974e9-7fe4-5c5b-a476-13925ff7bc45
DOI: 10.21954/ou.ro.0000f5df

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