Article
Human progelatinase A can be activated by matrilysin.
FEBS letters - 23 May 1994
Crabbe T, Smith B, O'Connell J, Docherty A
Abstract excerpt
The activation of human progelatinase A by other matrix metalloproteinases was studied by following both the loss of its N-terminal propeptide and the accompanying increase in the rate of hydrolysis of a synthetic substrate. Activated stromelysin 1 was unable to cause any activation of progelatinase A beyond that slowly occurring by autolysis, but an 8 h incubation with activated matrilysin was able to produce...
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