Article
Human progelatinase A can be activated by matrilysin.
FEBS letters - 23 May 1994
Crabbe T, Smith B, O'Connell J, Docherty A
Abstract excerpt
The activation of human progelatinase A by other matrix metalloproteinases was studied by following both the loss of its N-terminal propeptide and the accompanying increase in the rate of hydrolysis of a synthetic substrate. Activated stromelysin 1 was unable to cause any activation of progelatin...
Topics
- Amino Acid Sequence
- Enzyme Activation
- Enzyme Precursors
- Gelatinases
- Humans
- Matrix Metalloproteinase 7
- Metalloendopeptidases
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational
- Sequence Analysis
- Substrate Specificity