Nasal environment potentiates the pathogenicity of <i>Bordetella pertussis</i>

Abstract excerpt

Pertussis remains a major health concern, as acellular vaccines fail to prevent nasal infection and transmission. The nasal cavity is the primary niche for Bordetella pertussis colonization, but how this particular environment shapes bacterial pathogenicity remains poorly understood. Here we developed bacterial culture conditions that replicate the nasal environment, combining nasal-fluid-like transition metals c...

Topics

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• Bacterial Infections and Vaccines
• Bacterial Proteins
• Bordetella pertussis
• Gene Expression Regulation, Bacterial
• Infective Endocarditis Diagnosis and Management
• Macrophages
• Phenotype
• Whooping Cough

Identifiers and source

Literature Corpus work

2e49efbd-fc36-5267-adfc-c3cb9f58d501

DOI

10.64898/2026.07.14.738394