Article

Heterotypic Seeding Generates Mixed Amyloid Polymorphs

2024-03-17

Abstract excerpt

Aggregation of the amyloid β (Aβ) peptide into fibrils represents one of the major biochemical pathways underlying the development of Alzheimer’s disease (AD). Extensive studies have been carried out to understand the role of fibrillar seeds on the overall kinetics of amyloid aggregation. However, the precise effect of seeds that are structurally or sequentially different from Aβ on the structure of the resulting...

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Literature Corpus work: 2e119d11-8902-5af9-a86b-5888f45a1652
DOI: 10.1101/2024.03.15.585264

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