Article

A key axis of the N-WASP signaling pathway promotes distant metastasis in pancreatic cancer: LOXL2-FAK-N-WASP

2022-08-29

Abstract excerpt

<h4>Background: </h4> Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid malignancies. A specific mechanism of its metastasis is not established. In our present study, we investigated whether Neural Wiskott-Aldrich Syndrome Protein (N-WASP) plays a role in distant metastasis of PDAC. <h4>Methods: </h4> Pancreatic cancer cell lines MIA PaCa-2, PANC-1, AsPC-1, and BxPC-3 were used for in vit...

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Literature Corpus work: 2df0f76c-933a-5425-9951-9172500b937a
DOI: 10.21203/rs.3.rs-1992553/v1

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