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Overexpression of Laminin-5 Gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade

2022-04-12

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma (PDAC) is correlated with poor outcomes because of limited therapeutic options. Laminin-5 Gamma-2 (LAMC2) plays a critical role in key biological processes. However, the detailed molecular mechanism and potential roles of LAMC2 in PDAC stay unexplored. The present study examines the essential role and molecular mechanisms of LAMC2 in the tumorigenesis of...

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Literature Corpus work
8c449ff8-c123-5585-827f-c2d6f1135ad1
DOI
10.21203/rs.3.rs-1469104/v1
Open publication

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Overexpression of Laminin-5 Gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascadeDOI 10.21203/rs.3.rs-1469104/v1
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