Article
BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat.
Physiological genomics - 13 Apr 2006
Kwitek Anne E, Jacob Howard J, Baker John E, Dwinell Melinda R, Forster Hubert V, Greene Andrew S, Kunert Mary Pat, Lombard Julian H, Mattson David L, Pritchard Kirkwood A, Roman Richard J, Tonellato Peter J, Cowley Allen W
Abstract excerpt
The postgenome era has provided resources to link disease phenotypes to the genomic sequence, i.e., creating a disease "phenome." Our detailed characterization of the sequenced BN rat strain (BN/NHsdMcwi) provides the first concerted effort in creating a direct link between a sequenced genome and its resulting biology. For the BN sequence to be of broad value to investigators, these measures need to be put into...
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