Article

Single-cell characterization of transcriptomic heterogeneity in lymphoblastoid cell lines

2020-09-25

Abstract excerpt

Lymphoblastoid Cell Lines (LCLs) are generated by transforming primary B cells with Epstein-Barr Virus (EBV) and are used extensively as model systems in viral oncology, immunology, and human genetics research. In this study, we characterized single-cell transcriptomic profiles of five LCLs and present a simple discrete-time simulation to explore the influence of stochasticity on LCL clonal evolution. Single-cell...

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Literature Corpus work: 2db7763b-2ce5-5b84-9e93-e02e734d7249
DOI: 10.1101/2020.09.24.311886

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