Article

USP10 activates the FAK pathway by stabilizing RIOK3 in pancreatic ductal adenocarcinoma

2024-02-13

Abstract excerpt

<title>Abstract</title><p>Background The aberrant activation of FAK (Focal Adhesion Kinase) serves as a critical mechanism leading to heightened invasiveness and metastatic potential in pancreatic ductal adenocarcinoma (PDAC). FAK inhibitors have entered clinical trials, underscoring the significance of targeting FAK in treating PDAC. Further exploration of the regulation mechanism of FAK is crucial for advancing...

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Literature Corpus work: 2d840593-31e3-5cb6-abd9-3e6709bfe8f5
DOI: 10.21203/rs.3.rs-3941004/v1

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