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Article

Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC.

Biochemical and biophysical research communications - 15 May 2018

Cao Xiao-Yan, Zhang Xiao-Xin, Yang Min-Wei, Hu Li-Peng, Jiang Shu-Heng, Tian Guang-Ang, Zhu Li-Li, Li Qing, Sun Yong-Wei, Zhang Zhi-Gang

Abstract excerpt

Pancreatic Ductal Adenocarcinoma (PADC) metastasis is the leading cause of morality of this severe malignant tumor. Proteases are key players in the degradation of extracellular matrix which promotes the cascade of tumor metastasis. As a kind of serine proteases, the kallikrein family performs vital function on the cancer proteolysis scene, which have been proved in diverse malignant tumors. However, the specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29621546
DOI: 10.1016/j.bbrc.2018.03.194

Genes

KLK10
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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