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USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer

2024-06-28

Abstract excerpt

<title>Abstract</title> <p>The ubiquitin-specific protease (USP) family is the largest and most diverse deubiquitinase (DUBs) family and plays a significant role in maintaining cell homeostasis. Dysregulation of USPs has been associated with carcinogenesis of various tumors. We identified that USP19 was downregulated in pancreatic tumor tissues and forced expression of USP19 diminished tumorigenicity of pancreati...

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Literature Corpus work
e23499e6-b95f-5b5f-90b0-9bb1b901533b
DOI
10.21203/rs.3.rs-4512791/v1
Open publication

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USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancerDOI 10.21203/rs.3.rs-4512791/v1
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