Article

Gla-domain mediated targeting of externalized phosphatidylserine for intracellular delivery

2022-06-14

Abstract excerpt

Phosphatidylserine (PS) is a negatively charged phospholipid normally localized to the inner leaflet of the plasma membrane of cells but is externalized onto the cell surface during apoptosis as well as in malignant and infected cells. Consequently, PS may comprise an important molecular target in diagnostics, imaging and targeted delivery of therapeutic agents. While an array of PS binding-molecules exist, their...

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Literature Corpus work: 2d81ecb4-63cf-5dba-bfb6-bf1ade815e58
DOI: 10.1101/2022.06.13.495901

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