Article

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

2020-09-21

Abstract excerpt

<title>Abstract</title> <p>Patient-derived tumor xenograft (PDX)/organoid (PDO), driven by cancer stem cells (CSC), are considered the most predictive models for translational oncology. Large PDX collections reflective of patient populations have been created and used extensively to test various investigational therapies, including in population-trials as surrogate subjects in vivo. PDOs are recognized as in vitr...

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Literature Corpus work: 2d642fce-0f6d-592e-9224-7aae604bfd40
DOI: 10.21203/rs.3.rs-63366/v1

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