Article

A sensor of oxidative stress confers virulence via response memory in Acinetobacter baumannii

2026-04-09

Abstract excerpt

All living organisms must adapt to environmental stresses to survive. The two-component system (TCS) is a prevalent signal transduction mechanism to alter gene expression in response to stress in bacteria. We report that the PmrB sensor of the PmrA/PmrB TCS senses sublethal oxidative stress and encodes a response memory that promotes virulence in Acinetobacter baumannii. PmrB detects oxidative stress through histi...

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Literature Corpus work: 2d5225be-bf1f-558c-a5de-038a9beac5a8
DOI: 10.64898/2026.04.08.717352

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