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Prominent transcriptomic changes in Mycobacterium intracellulare under acidic and oxidative stress

17 Apr 2024

Abstract excerpt

BACKGROUND: Mycobacterium avium complex (MAC), including Mycobacterium intracellulare is a member of slow-growing mycobacteria and contributes to a substantial proportion of nontuberculous mycobacterial lung disease in humans affecting immunocompromised and elderly populations. Adaptation of pathogens in hostile environments is crucial in establishing infection and persistence within the host. However, the...

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PMID: 38632539
DOI: 10.1186/s12864-024-10292-4

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