Article

TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway

2020-10-12

Abstract excerpt

Bladder cancer is one of the most prevalent cancer types in the world, frequently exhibiting invasion and metastasis and therefore associated with poor prognosis. It is a progressive disease with high recurrence rates even after surgery, which calls for the urgent need for early intervention and diagnosis. The E3 ubiquitin ligase TNF Receptor Associated Factor 4 (TRAF4) has been largely implicated as a tumour-prom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2d4736da-5f03-588b-88f4-aea4dd3aec51
DOI: 10.1101/2020.10.12.335588

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathwayDOI 10.1101/2020.10.12.335588Read

Ubiquitination Degraded BMPR2 By Smurf1 Promotes Bladder Cancer Cell GrowthSemantic proximity Read

Increased expression of TNFRSF14 indicates good prognosis and inhibits bladder cancer proliferation by promoting apoptosisSemantic proximity Read

Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells.Semantic proximity Read

Ubiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivinSemantic proximity Read

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated mannerSemantic proximity Read

MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 proteinSemantic proximity Read

Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosisSemantic proximity Read

The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking statusSemantic proximity Read

STAMBP-Mediated K63 Deubiquitination of E2F1 Release E2F1 from RB Repressive Complex to Drive Bladder Cancer ProgressionSemantic proximity Read

Activating transcription factor 5 (ATF5) promotes tumorigenic capability and activates the Wnt/b-catenin pathway in bladder cancerSemantic proximity Read

KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2Semantic proximity Read

SOX4 regulates invasion of bladder cancer cells via repression of WNT5aSemantic proximity Read