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Activating transcription factor 5 (ATF5) promotes tumorigenic capability and activates the Wnt/b-catenin pathway in bladder cancer

1 Dec 2021

Abstract excerpt

Abstract Background In bladder cancer, up to 70% of patients will relapse after resection within 5 years, in which the mechanism underlying the recurrence remains largely unclear. Methods Quantitative real-time PCR, western blot and immunohistochemistry were conducted. The assays of tumor sphere formation and tumor xenograft were further performed to assess the potential biological roles of ATF5 (activating...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 34895217
DOI: 10.1186/s12935-021-02315-x

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