Article

m 6 A demethylase ALKBH5 regulates TP53 to promote malignant transformation of lung cells induced by radon exposure via BTG2-mediated mitochondrial pathway

2024-01-18

Abstract excerpt

<title>Abstract</title> <p>Lung cancer is a multi-etiological disease and radon is known as the second most common risk factor for the disease. The tumor suppressor gene <italic>TP53</italic> is commonly mutated in human lung cancer, thus contributing to the alteration of mitochondrial outer membrane permeability (MOMP). Thus, this study aimed to investigate the role of the P53-mediated mitochondrial pathway in r...

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Literature Corpus work: 2d3bad08-6e3c-5626-8404-18ad4de17bd0
DOI: 10.21203/rs.3.rs-3864065/v1

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m 6 A demethylase ALKBH5 regulates TP53 to promote malignant transformation of lung cells induced by radon exposure via BTG2-mediated mitochondrial pathwayDOI 10.21203/rs.3.rs-3864065/v1Read

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