Article

Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stress

2022-06-12

Abstract excerpt

<h4>ABSTRACT</h4> Oxidative stress is associated with cardiovascular and neurodegenerative diseases, diabetes, cancer, psychiatric disorders and aging. In order to counteract, eliminate and/or adapt to the sources of stress, cells possess elaborate stress-response mechanisms, which also operate at the level of regulating transcription. Interestingly, it is becoming apparent that the metabolic state of the cell an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2d1dea30-43be-5a63-906a-23407a32932b
DOI: 10.1101/2022.06.12.495787

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stressDOI 10.1101/2022.06.12.495787Read

Functional and Regulatory Profiling of Energy Metabolism in Fission YeastSemantic proximity Read

Genome-wide Screening of Regulators of Catalase Expression: ROLE OF A TRANSCRIPTION COMPLEX AND HISTONE AND tRNA MODIFICATION COMPLEXES ON ADAPTATION TO STRESS.Semantic proximity Read

Genomic binding profiling of the fission yeast stress-activated MAPK Sty1 and the bZIP transcriptional activator Atf1 in response to H2O2.Semantic proximity Read

Functional and regulatory profiling of energy metabolism in fission yeast.Semantic proximity Read

Characterization of global gene expression during assurance of lifespan extension by caloric restriction in budding yeast.Semantic proximity Read

Tra1 controls the transcriptional landscape of the aging cell.Semantic proximity Read

Time-Course Analysis of Gene Expression During theSaccharomyces cerevisiaeHypoxic ResponseSemantic proximity Read

Phospho-mimicking Atf1 mutants bypass the transcription activating function of the MAP kinase Sty1 of fission yeast.Semantic proximity Read

Molecular mechanism of the multiple regulation of the Saccharomyces cerevisiae ATF1 gene encoding alcohol acetyltransferase.Semantic proximity Read

An ATF4-centric regulatory network is required for the assembly and function of the OXPHOS systemSemantic proximity Read

The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.Semantic proximity Read

H2A.Z-dependent and -independent recruitment of metabolic enzymes to chromatin required for histone modificationsSemantic proximity Read