Article

Advancing Age and the rs6265 BDNF SNP are Permissive to Graft-induced Dyskinesias in Parkinsonian Rats

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>The rs6265 single nucleotide polymorphism (SNP) in the gene for brain-derived neurotrophic factor is a common variant that alters therapeutic outcomes for individuals with Parkinson’s disease (PD). We previously investigated the effects of this SNP on the experimental therapeutic approach of neural grafting, demonstrating that young adult parkinsonian rats carrying the variant Met allel...

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Literature Corpus work: 2ce3b623-b25c-5f32-9bc0-964692bf27c8
DOI: 10.21203/rs.3.rs-4243843/v1

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