Article

Neuroinflammation distinguishes HLA haplotypes in progressive supranuclear palsy

2025-07-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Progressive supranuclear palsy (PSP) is a neurodegenerative 4R tauopathy clinically presenting with atypical parkinsonism or cognitive behavioral changes and a relatively uniform neuropathology. We recently identified rare HLA haplotypes in PSP and now examine whether HLA haplotypes are associated with different cytopathological and clinical phenotypes. <h4>Methods</h4> Ret...

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Literature Corpus work: 2ccf472d-4bbc-578d-bfbe-f560171cf8e3
DOI: 10.1101/2025.07.21.25331869

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