Article

Identification of post-transcriptional modifications in nucleic acid sequences using purpose-designed molecular beacons

2023-05-25

Abstract excerpt

Post-transcriptional RNA modifications (PTxMs) present in small RNA species, specifically circulating extracellular RNAs, were recently identified as clinically relevant readouts, often more indicative of disease severity than the classical “up and down” changes in their copy number alone. While identification of PTxMs requires multiple and complex sample preparation steps, microgram-range amounts of RNA, followed...

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Literature Corpus work: 2cc8bdfa-e0e3-59ad-98a3-6e2464875f62
DOI: 10.1101/2023.05.25.542360

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