Article

<i>In silico Drosophila Patient Model</i> Reveals Optimal Combinatorial Therapies for Colorectal Cancer

2020-09-01

Abstract excerpt

In silico models of biomolecular regulation in cancer, annotated with patient-specific gene expression data can aid in the development of novel personalized cancer therapeutics strategies. Drosophila melanogaster is a well-established animal model that is increasingly being employed to evaluate preclinical personalized cancer therapies. Here, we report five Boolean network models of biomolecular regulation in cel...

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Literature Corpus work: 2cb31457-725f-560a-b041-3137d77607e5
DOI: 10.1101/2020.08.31.274829

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