Article

Malic enzyme 1 may be a novel target of breast cancer metastasis

2019-10-18

Abstract excerpt

<title>Abstract</title> <p>Background Malic enzyme 1 (ME1) catalyzes malate to pyruvate and thus promotes glycolysis, playing a part in the Warburg effect. It also has a potential role in tumor progression, but its function in breast cancer remains to be fully clarified. This work aimed to investigate the prognostic value of ME1 and its possible mechanism in breast cancer.Methods We evaluated ME1 expression in 22...

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Literature Corpus work: 2c7d1c70-a434-5b02-88d8-d4af7f094aab
DOI: 10.21203/rs.2.16238/v1

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