Article

Mechanism of Metabolic Disorder and Endothelial Dysfunction in Alzheimer’s Disease

2026-06-15

Abstract excerpt

Alzheimer’s disease (AD) remains the most common cause of dementia worldwide and one of the greatest health challenges of the twenty-first century. Traditionally viewed as a neurodegenerative disorder defined by amyloid-β plaques and tau tangles, recent evidence implicates systemic metabolic dysfunction and endothelial injury as key drivers of the disease progression. Insulin resistance, dyslipidemia, and chronic...

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Literature Corpus work: ba5586ef-9158-5b4d-8267-f5d5f5b8ab08
DOI: 10.12688/f1000research.172489.2

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