Article

Mechanism of Metabolic Disorder and Endothelial Dysfunction in Alzheimer’s Disease

2025-12-26

Abstract excerpt

Alzheimer’s disease (AD) remains the most common cause of dementia worldwide and one of the greatest health challenges of the twenty-first century. Traditionally viewed as a neurodegenerative disorder defined by amyloid-β plaques and tau tangles, recent evidence implicates systemic metabolic dysfunction and endothelial injury as key drivers of the disease progression. Insulin resistance, dyslipidemia, and chronic...

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Literature Corpus work: 4d5390fd-f710-5a27-9dde-1cf44ce517e4
DOI: 10.12688/f1000research.172489.1

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