Article

Oligodendrocyte Dysfunction to Autoimmune Pathology in Multiple Sclerosis

2025-07-03

Abstract excerpt

The prevailing view for the onset of Multiple Sclerosis is that it is an “outside-in” driven pathology. It's believed that primary infection with Epstein Barr Virus (EBV) in those with a genetic susceptibility to MS, drives the production of auto-reactive B cells that infiltrate the Central Nervous System from the periphery and seed the CNS with EBV. Upon infection of the CNS with EBV, an autoimmune response to th...

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Literature Corpus work: 2c488152-1166-5751-970d-7cc63735c1c9
DOI: 10.20944/preprints202507.0322.v1

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