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Article

Multiple sclerosis: an example of pathogenic viral interaction?

28 Feb 2017

Abstract excerpt

A hypothesis is formulated on viral interaction between HHV-6A and EBV as a pathogenic mechanism in Multiple Sclerosis (MS). Evidence of molecular and genetic mechanisms suggests a link between HHV-6A infection and EBV activation in the brain of MS patients leading to intrathecal B-cell transformation. Consequent T-cell immune response against the EBV-infected cells is postulated as a pathogenic basis for...

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PMID: 28241767
DOI: 10.1186/s12985-017-0719-3

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