Article

A novel combinatorial treatment for Neurofibromatosis type 1 tumours revealed through cross-species genetic analysis

2026-08-21

Abstract excerpt

Abstract Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder associated with a wide range of symptoms, including the formation of tumours along nerves. These tumours can affect nerve function, leading to pain and loss of sensory or motor capacity. Drug treatments are currently limited, and relatively few new targets have emerged for NF1 tumours despite intensive research. Therefore, new drugs to targe...

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Literature Corpus work: 2c310383-94b5-5122-a039-5dcb2899cbe2
DOI: 10.1038/s41389-026-00643-z

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