Article

Suppression of mitochondrial heterogeneity via engineered mitochondria for reversion of mitochondrial disease-related phenotypes

2022-12-12

Abstract excerpt

<title>Abstract</title> <p>Mitochondrial heterogeneity above the biochemical threshold (~50% damaged mitochondria load) induces the symptom manifest of multiple mitochondrial diseases without effective treatment. However, current mitochondria-targeted therapies related to mitochondrial heterogeneity regulation have yielded unsatisfactory clinical incomes due to the risk of damaged mitochondria carryover and the i...

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Literature Corpus work: 2c300f58-0467-5621-bca0-113ed65a8d10
DOI: 10.21203/rs.3.rs-2327478/v1

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