Article

The circadian clock protein REVERBα inhibits pulmonary fibrosis development

2019-09-25

Abstract excerpt

Pulmonary inflammatory responses lie under circadian control; however the importance of circadian mechanisms in fibrosis is not understood. Here, we identify a striking change to these mechanisms resulting in a gain of amplitude and lack of synchrony within pulmonary fibrotic tissue. These changes result from an infiltration of mesenchymal cells, an important cell type in the pathogenesis of pulmonary fibrosis. Mu...

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Literature Corpus work: 2c253b4b-2748-5cfc-962d-b6dea43171db
DOI: 10.1101/781666

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