Article
Drug tolerant persister cell plasticity in cancer: a revolutionary strategy for more effective anticancer therapies
13 Aug 2024
Abstract excerpt
Non-genetic mechanisms have recently emerged as important drivers of anticancer drug resistance. Among these, the drug tolerant persister (DTP) cell phenotype is attracting more and more attention and giving a predominant non-genetic role in cancer therapy resistance. The DTP phenotype is characterized by a quiescent or slow-cell-cycle reversible state of the cancer cell subpopulation and inert specialization to...
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