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Accessible CKD Risk Index (ACRI): A Genetically Anchored, Mechanistically Validated, Income-Agnostic Early Detection Score for Chronic Kidney Disease - A Pan-Cohort Study Across Five Global Income Settings

2026-05-09

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<title>Abstract</title> <p> Background: Chronic kidney disease (CKD) affects approximately 850 million individuals worldwide and is frequently diagnosed only at stage 3–4, when over 50% of nephron mass is already lost. Current standard markers - serum creatinine and estimated glomerular filtration rate (eGFR) - lack early sensitivity. We developed and validated the Accessible CKD Risk Index (ACRI), a five-marke...

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Literature Corpus work
2bd8098d-5570-5160-8fa3-fd350ff49475
DOI
10.21203/rs.3.rs-9569113/v1
Open publication

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Accessible CKD Risk Index (ACRI): A Genetically Anchored, Mechanistically Validated, Income-Agnostic Early Detection Score for Chronic Kidney Disease - A Pan-Cohort Study Across Five Global Income SettingsDOI 10.21203/rs.3.rs-9569113/v1
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