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Article

Loss of β-cell identity in diabetes : significance of miR-7-mediated chromatin remodelling

2020-01-01

Abstract excerpt

Type 2 diabetes (T2D) affects 10% of the adult global population and is a multifactorial disease characterised by insulin resistance of peripheral organs. Insulin resistance results eventually in failure of pancreatic β-cells and subsequent apoptosis. Recent research revealed that β-cell dedifferentiation is contributing to decreasing their function in T2D. Dedifferentiated β-cells express atypical non-β-cell horm...

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Literature Corpus work
2bd1d544-8800-5885-8ca0-d1792cd84d38
DOI
10.25560/85551
Open publication

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Loss of β-cell identity in diabetes : significance of miR-7-mediated chromatin remodellingDOI 10.25560/85551
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