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Article

Pancreas-enriched miRNA refines endocrine cell differentiation

5 Jul 2012

Abstract excerpt

Genome-encoded microRNAs (miRNAs) provide a post-transcriptional regulatory layer that is important for pancreas development. However, how specific miRNAs are intertwined into the transcriptional network, which controls endocrine differentiation, is not well understood. Here, we show that microRNA-7 (miR-7) is specifically expressed in endocrine precursors and in mature endocrine cells. We further demonstrate...

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PMID: 22764048
DOI: 10.1242/dev.080127

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