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MicroRNAs in β-Cell Biology, Insulin Resistance, Diabetes and Its Complications

20 Jun 2011

Abstract excerpt

MicroRNAs (miRNAs) are small 19-23 nucleotide RNA molecules that act as regulators of protein expression in eukaryotic cells by inducing the translations] arrest and degradation of messenger RNAs (1). They are potent drivers of differentiation and development (1), and their dysregulation has been linked to many diseases. Here, we present an overview of the known and proposed roles and effects of miRNAs in type 1...

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PMID: 21709277
DOI: 10.2337/db11-0171

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