Article

Forward genetics reveals microsporidian drug targets and recombination-based resistance

2026-01-30

Abstract excerpt

Microsporidia are a diverse group of intracellular fungal parasites that infect humans and many agriculturally important animals. Several microsporidia inhibitors have been characterized, but the targets of these inhibitors in microsporidia have not been confirmed, and the mechanisms by which microsporidia evolve resistance are unknown. Using the model organism Caenorhabditis elegans and its naturally occurring m...

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Literature Corpus work: 2ba88c1c-de82-5ce9-ac28-3e27ebc65f9f
DOI: 10.64898/2026.01.30.702766

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