Article
A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidian parasite.
PLoS pathogens - 1 Feb 2015
Balla Keir M, Andersen Erik C, Kruglyak Leonid, Troemel Emily R
Abstract excerpt
Microbial pathogens impose selective pressures on their hosts, and combatting these pathogens is fundamental to the propagation of a species. Innate immunity is an ancient system that provides the foundation for pathogen resistance, with epithelial cells in humans increasingly appreciated to play key roles in innate defense. Here, we show that the nematode C. elegans displays genetic variation in epithelial...
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