Article

Association of <i>SAPAP3</i> allelic variants with symptom dimensions and pharmacological treatment response in obsessive-compulsive disorder

2020-03-12

Abstract excerpt

<h4>Background</h4> Though several SAPAP3 gene knockout studies in mice have implicated its role in compulsivity, human studies have failed to demonstrate its association with obsessive-compulsive disorder (OCD). We examined the association between allelic variants of a single nucleotide polymorphism in the SAPAP3 gene (rs6662980) with specific aspects of the OCD phenotype. <h4>Methods</h4> A total of 200 subjects...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2b866224-f914-521a-9e4a-0dcadcc39847
DOI: 10.1101/2020.03.07.20032391

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association of <i>SAPAP3</i> allelic variants with symptom dimensions and pharmacological treatment response in obsessive-compulsive disorderDOI 10.1101/2020.03.07.20032391Read

Association of SAPAP3 allelic variants with symptom dimensions and pharmacological treatment response in obsessive-compulsive disorder.Semantic proximity Read

Common variants of HTR3 genes are associated with obsessive-compulsive disorder and its phenotypic expression.Semantic proximity Read

Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population.Semantic proximity Read

Exploring genetic variants in obsessive compulsive disorder severity: A GWAS approach.Semantic proximity Read

Genetic susceptibility in obsessive-compulsive disorder.Semantic proximity Read

Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.Semantic proximity Read

Looking into the genetic bases of OCD dimensions: a pilot genome-wide association study.Semantic proximity Read

Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin TreatmentSemantic proximity Read

Genetics of obsessive-compulsive disorder.Semantic proximity Read

Genetic meta-analysis of obsessive-compulsive disorder and self-report compulsive symptoms.Semantic proximity Read

Correlations between single nucleotide polymorphisms in obsessive-compulsive disorder with the clinical features or response to therapy.Semantic proximity Read

BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response.Semantic proximity Read