Article
Genetic meta-analysis of obsessive-compulsive disorder and self-report compulsive symptoms.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2020
Smit Dirk J A, Cath Danielle, Zilhão Nuno R, Ip Hill F, Denys Damiaan, den Braber Anouk, de Geus Eco J C, Verweij Karin J H, Hottenga Jouke-Jan, Boomsma Dorret I
Abstract excerpt
We investigated whether obsessive-compulsive (OC) symptoms from a population-based sample could be analyzed to detect genetic variants influencing obsessive-compulsive disorder (OCD). We performed a genome-wide association studies (GWAS) on the obsession (rumination and impulsions) and compulsion (checking, washing, and ordering/precision) subscales of an abbreviated version of the Padua Inventory (N = 8,267 with...
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