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Article

Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2009

Bienvenu O J, Wang Y, Shugart Y Y, Welch J M, Grados M A, Fyer A J, Rauch S L, McCracken J T, Rasmussen S A, Murphy D L, Cullen B, Valle D, Hoehn-Saric R, Greenberg B D, Pinto A, Knowles J A, Piacentini J, Pauls D L, Liang K Y, Willour V L, Riddle M, Samuels J F, Feng G, Nestadt G

Abstract excerpt

SAP90/PSD95-associated protein (SAPAP) family proteins are post-synaptic density (PSD) components that interact with other proteins to form a key scaffolding complex at excitatory (glutamatergic) synapses. A recent study found that mice with a deletion of the Sapap3 gene groomed themselves excess...

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Identifiers

PMID: 19051237
DOI: 10.1002/ajmg.b.30897
PMCID: PMC10885776

Genes

PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19051237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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