Article

Bistability to Quad-stability: Emergence of Hybrid Phenotypes & Enhanced Spatio-temporal Plasticity in Presence of Host-Circuit Coupling

2026-02-15

Abstract excerpt

In the context of multistability-driven diseases, like cancer, spatio-temporal plasticity plays a significant role to achieve a spectrum of phenotypic variations. The interplay between gene regulatory networks and environmental factors, such as resource competition and spatial diffusion, plays a crucial role in determining cellular behaviour and phenotypic heterogeneity. Though reaction–diffusion frameworks have b...

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Literature Corpus work: 2b8545bc-f258-5057-8857-73506936f3d2
DOI: 10.64898/2026.02.12.705673

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