Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Local and global features of genetic networks supporting a phenotypic switch.

PloS one - 1 Jan 2020

Shomar Aseel, Barak Omri, Brenner Naama

Abstract excerpt

Phenotypic switches are associated with alterations in the cell's gene expression profile and are vital to many aspects of biology. Previous studies have identified local motifs of the genetic regulatory network that could underlie such switches. Recent advancements allowed the study of networks at the global, many-gene, level; however, the relationship between the local and global scales in giving rise to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Variation, Population
Share to Epithelial-Mesenchymal Transition
Share to Feedback, Physiological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Models, Biological

Share to Models, Genetic

Share to Models, Statistical

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 32881964
DOI: 10.1371/journal.pone.0238433
PMCID: PMC7470255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Local and global features of genetic networks supporting a phenotypic switch.PMID 32881964Read ↗

Robustness in phenotypic plasticity and heterogeneity patterns enabled by EMT networks.Semantic proximity Read ↗

Landscape of epithelial-mesenchymal plasticity as an emergent property of coordinated teams in regulatory networks.Semantic proximity Read ↗

Multistability in the epithelial-mesenchymal transition network.Semantic proximity Read ↗

Identifying inhibitors of epithelial-mesenchymal plasticity using a network topology-based approach.Semantic proximity Read ↗

The Many-Faced Program of Epithelial–Mesenchymal Transition: A System Biology-Based ViewSemantic proximity Read ↗

The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation.Semantic proximity Read ↗

Topological signatures in regulatory network enable phenotypic heterogeneity in small cell lung cancerSemantic proximity Read ↗

Network topology metrics explaining enrichment of hybrid epithelial/mesenchymal phenotypes in metastasis.Semantic proximity Read ↗

Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancerSemantic proximity Read ↗

Topological signatures in regulatory network enable phenotypic heterogeneity in small cell lung cancer.Semantic proximity Read ↗

Topography of epithelial-mesenchymal plasticity.Semantic proximity Read ↗

Principles of dynamical modularity in biological regulatory networks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.