Article
Abrupt transitions to tumor extinction: a phenotypic quasispecies model.
Journal of mathematical biology - 1 Jun 2017
Sardanyés Josep, Martínez Regina, Simó Carles, Solé Ricard
Abstract excerpt
The dynamics of heterogeneous tumor cell populations competing with healthy cells is an important topic in cancer research with deep implications in biomedicine. Multitude of theoretical and computational models have addressed this issue, especially focusing on the nature of the transitions governing tumor clearance as some relevant model parameters are tuned. In this contribution, we analyze a mathematical model...
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