Article

Structural variants contribute substantially to complex trait heritability

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Background: Despite accumulating evidence that structural variants (SVs) exert disproportionate functional effects, their genome-wide contribution to complex trait heritability has not yet been systematically quantified. Here, we introduce MiXeR-SV, a tool that integrates long-read-derived SVs from existing reference catalogs with genome-wide association summary statistics to quantify S...

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Literature Corpus work: 2b2a41fc-48bc-5b6e-b3a3-09f31e470a1c
DOI: 10.21203/rs.3.rs-9226299/v1

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